Abstract
Mass vaccination using newly approved vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has begun globally. However, their effect on fertility have not yet been investigated. Previous studies demonstrate that SARS-CoV-2 infection may impair sperm parameters. In this study, we are the first to assess the effect of the BNT162b2 mRNA Covid-19 vaccine on sperm parameters. Our results demonstrate that the vaccine does not impair sperm parameters. Thus, we recommend that couples desiring to conceive should vaccinate, as vaccination does not affect sperm whereas SARS-CoV-2 infection does impair sperm.
Introduction
Mass vaccination using newly approved vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has begun globally. To eradicate this disease, vaccination of the younger population is recommended (1). A number of clinical trials have been done to assess the safety of these vaccines, however, their effect on fertility have not yet been investigated (2). Nevertheless, the Task Force does not recommend withholding vaccines from patients who are planning to conceive (3). Furthermore, the gonads may potentially be vulnerable to SARS-CoV-2 infection (4), and several studies found a significantly negative impact of SARS-CoV-2 infection on sperm parameters (5).
Full Article
To read the full version of this paper, click here.